Recent Advances in Polyphenol Research, Volume 8

Recent Advances in Polyphenol Research, Volume 8

Quideau, Stephane; Salminen, Juha-Pekka; de Freitas, Victor; Wahala, Kristiina

John Wiley and Sons Ltd

03/2023

416

Dura

Inglês

9781119844761

15 a 20 dias

Descrição não disponível.
Contributors

Preface

Acknowledgements

1 Lignins and Lignification: New Developments and Emerging Concepts
John Ralph, Hoon Kim, Fachuang Lu, Rebecca A. Smith, Steven D. Karlen, Nuoendagula, Koichi Yoshioka, Alexis Eugene, Sarah Liu, Canan Sener, Daisuke Ando, Mingjie Chen, Yanding Li, Leta L. Landucci, Sally A. Ralph, Vitaliy I. Timokhin, Wu Lan, Jorge Rencoret, Jose C. del Rio

1.1 Introduction

1.2 The monolignol pathway and interacting pathways -- New lignins

1.3 Lignin conjugates, 'clip-offs' -- new discoveries, and enhancing levels

1.4 Features of lignification, and the possibility of new polymerization pathways

1.5 The value of model studies and synthesis -- a reminder

1.6 New or improved analytics

1.7 Conclusions and Opportunities

2 Synthesis of epigallocatechin gallate, nobiletin and their derivatives for chemical-biology studies
Tomohiro Asakawa, Makoto Inai and Toshiyuki Kan

2.1 Synthetic investigations of catechin derivatives

2.2 Synthesis and application of fluorescent catechin probes

2.3 Generation of catechin antibody

2.4 PET imaging of biodistribution of catechin

2.5 Practical synthesis of nobiletin

2.6 Derivatization of desmethyl nobiletins

2.7 PET imaging of biodistribution of nobiletin

2.8 Synthesis and application of fluorescent nobiletin probe

2.9 Conclusions

3 Procyanidins in the Onset and Progression of Colorectal Cancer: Recent Advances and Open Questions
Wei Zhu, Gerardo G. Mackenzie and Patricia I. Oteiza

3.1 Introduction

3.2 Procyanidins:chemistry and metabolism

3.3 Procyanidins and CRC: epidemiological evidence

3.4 Procyanidins and CRC: rodent studies

3.5 Procyanidins and CRC: mechanisms of actions

3.6 Conclusions and open questions

3.7 Acknowledgements

4 The Potential of Low Molecular Weight (Poly)phenol Metabolites for Attenuating Neuroinflammation and Treatment of Neurodegenerative Diseases
Daniela Marques, Rafael Carecho, Diogo Carregosa and Claudia Nunes dos Santos

4.1 Introduction - Neurodegenerative disorders, dietary (poly)phenols and neuroinflammation

4.2 (Poly)phenols metabolism and distribution

4.3 (Poly)phenol metabolites and their brain permeability

4.4 LMW (poly)phenols metabolites as effectors for attenuating neuroinflammation

4.5 Concluding remarks

5 Deciphering Complex Natural Mixtures through Metabolome Mining of Mass Spectrometry Data: the Plant Specialized Metabolome as a Case Study
Justin J.J. van der Hooft, Madeleine Ernst, Daniel Papenberg, Kyo Bin Kang, Iris F. Kappers, Marnix H. Medema, Pieter C. Dorrestein, and Simon Rogers

5.1 Introduction

5.2 Materials and methods

5.3 Results and discussion

5.4 Current limitations

5.5 Conclusions

5.6 Outlook

5.7 Acknowledgements

6 Application of MS-based Metabolomics to Investigate Biomarkers of Apple Consumption Resulting from Microbiota and Host Metabolism Interactions
Fulvio Mattivi and Maria M. Ulaszewska

6.1 Introduction

6.2 Materials and methods

6.3 Results and discussion

6.4 Conclusions

7 Non-extractable polyphenols should be systematically included in polyphenols analysis
Enrique Baez-Garcia, Sonia G. Sayago-Ayerdi and Jara Perez-Jimenez

7.1 Introduction: the concept of non-extractable polyphenols

7.2 Analysis of non-extractable polyphenols

7.3 Why should non-extractable polyphenols be systematically included in polyphenol analysis?

7.4 Relevance of the determination of non-extractable polyphenols in quality control

7.5. Perspectives

8 Template-mediated engineering of functional metal--phenolic complex coatings
Steve Spoljaric, J.J. Richardson, Yi Ju, Frank Caruso

8.1 Introduction

8.2 Template-mediated techniques to deposit MPNs

8.3 MPN film properties

8.4 MPN surface interactions and applications

8.5 Upscaling considerations and challenges

8.6 Method automation: possibilities and outlook

8.7 Conclusions

9 Highly Efficient Production of Dihydroflavonol 4-Reductases in Tobacco Cells and Refinement of the BuOH-HCl Enzymatic Assay
Lingping Zhu, Saku Mattila, Roosa Matomaeki, Lorenzo Mollo, Sharmin Ahamed, Sara M. Abdou, Hany Bashandy and Teemu H. Teeri

9.1 Introduction

9.2 Results

9.3 Materials and methods

9.4 Discussion

10 A long and winding road: the evolution of transcriptional regulation of polyphenol biosynthesis
Cathie Martin, Jie Li and Nick W. Albert

10.1 Introduction

10.2 The importance of R2R3Myb transcription factors (TFs) in the regulation of phenylpropanoid metabolism in plants

10.3 The role of bHLH proteins in the regulation of phenylpropanoid metabolism

10.4 The role of the WDR in the MBW complex in the regulation of polyphenol metabolism

10.5 Additional factors regulating transcriptional control of the MBW complex

10.6 Conclusions

10.7 Acknowledgements

11 Analysis of Proanthocyanidins in Food Ingredients by the 4-(Dimethylamino)cinnamaldehyde Reaction
Daniel Esquivel-Alvarado, Emilia Alfaro-Viquez, Andrew Birmingham, Abigail Kramschuster, Christian G. Krueger, and Jess D. Reed

11.1. Introduction

11.2. Background on the 4-(dimethylamino)cinnalmaldehyde (DMAC) reaction with PACs

11.3. Mechanism of the acid catalyzed DMAC reaction with PACs

11.4 Absorption and emission spectra of the DMAC reaction products

11.5 Standards for the DMAC reaction and accuracy of the method

11.6 Interaction of PAC-DMAC reaction products with Extra-Intestinal Pathogenic Escherichia coli

11.7 Conclusions

12 Reactions of Ellagitannins Related to their Metabolism in Higher Plants
Takashi Tanaka

12.1 Introduction

12.2 Structural variety of ellagitannin acyl groups

12.3 Reactions of the DHHDP group

12.4 Decomposition of 1,4-DHHDP-?-D-glucose

12.5 Amariin as a precursor of geraniin

12.6 Triterpene HHDP esters in Castanopsis sieboldii

12.7 Highly-oxidized ellagitannins in Carpinus japonica

12.8 Similarity of catechin oxidation to oxidation of methyl gallate

12.9 Production mechanism of DHHDP and HHDP

12.10 Oxidative degradation of ellagitannins

12.11 Conclusions

References

Index
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Polyphenols; biosynthesis; flavonoids; proanthocyanidins; catechins; nobiletin; ellagitannins; lignins; metabolomics; neuroinflammation