Abnormal Chromosomes
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portes grátis
Abnormal Chromosomes
The Past, Present, and Future of Cancer Cytogenetics
Mitelman, Felix; Heim, Sverre
John Wiley and Sons Ltd
03/2022
208
Dura
Inglês
9781119651987
15 a 20 dias
464
Descrição não disponível.
Preface vii
Part I Past 1
Chapter 1 Understanding Disease: Ancient Theories 3
Chapter 2 The Advent of Cellular Pathology 7
Chapter 3 The Colored Bodies of Cell Nuclei: Chromosomes and Heredity 15
Chapter 4 Boveri and the Somatic Mutation Theory of Cancer 23
Chapter 5 Cytogenetics from 1914 to 1960: Slow Progress Followed by Serendipitous Methodological Breakthroughs Leading to Important Discoveries 29
Chapter 6 The First Cancer-Specific Chromosome Aberrations: Ph1 and Others 41
Part II Present 57
Chapter 7 The Banding Revolution: Cancer Cytogenetics in the 1970s 59
Chapter 8 Chasing Correlations: Chromosomes and Oncogenes in Leukemias and Lymphomas 75
Chapter 9 Solid Tumor Cytogenetics 87
Chapter 10 Gains, Losses, and Rearrangements of Genomic Material: Pathogenetic Considerations 105
Chapter 11 Morphology Meets Chemistry: Integration of Molecular Genetics into the Cytogenetic Search for Cancer-Specific Chromosome Aberrations 117
Chapter 12 Unraveling the Clonal Evolution of Neoplastic Cell Populations 125
Chapter 13 Clinical Usefulness 137
Part III Future 149
Chapter 14 Toward a Pathogenetic Classification of Cancer 151
Chapter 15 Where There is Structure, There is Function 161
Chapter 16 Which Resolution Level is Optimally Suited to
Answer Which Questions? Seeing Never Goes Out of Fashion . . . 169
Chapter 17 Are New Technical Breakthroughs on the Horizon? 179
Afterthoughts 189
Index 195
Part I Past 1
Chapter 1 Understanding Disease: Ancient Theories 3
Chapter 2 The Advent of Cellular Pathology 7
Chapter 3 The Colored Bodies of Cell Nuclei: Chromosomes and Heredity 15
Chapter 4 Boveri and the Somatic Mutation Theory of Cancer 23
Chapter 5 Cytogenetics from 1914 to 1960: Slow Progress Followed by Serendipitous Methodological Breakthroughs Leading to Important Discoveries 29
Chapter 6 The First Cancer-Specific Chromosome Aberrations: Ph1 and Others 41
Part II Present 57
Chapter 7 The Banding Revolution: Cancer Cytogenetics in the 1970s 59
Chapter 8 Chasing Correlations: Chromosomes and Oncogenes in Leukemias and Lymphomas 75
Chapter 9 Solid Tumor Cytogenetics 87
Chapter 10 Gains, Losses, and Rearrangements of Genomic Material: Pathogenetic Considerations 105
Chapter 11 Morphology Meets Chemistry: Integration of Molecular Genetics into the Cytogenetic Search for Cancer-Specific Chromosome Aberrations 117
Chapter 12 Unraveling the Clonal Evolution of Neoplastic Cell Populations 125
Chapter 13 Clinical Usefulness 137
Part III Future 149
Chapter 14 Toward a Pathogenetic Classification of Cancer 151
Chapter 15 Where There is Structure, There is Function 161
Chapter 16 Which Resolution Level is Optimally Suited to
Answer Which Questions? Seeing Never Goes Out of Fashion . . . 169
Chapter 17 Are New Technical Breakthroughs on the Horizon? 179
Afterthoughts 189
Index 195
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Cancer cytogenetic history; future of cancer cytogenetics; cancer cytogenetics impact; cancer cytogenetics influence; cancer cytogeneticclassification; cancer cytogenetic technology; cancer cytogenetic applications; cancer cytogeneticstructure
Preface vii
Part I Past 1
Chapter 1 Understanding Disease: Ancient Theories 3
Chapter 2 The Advent of Cellular Pathology 7
Chapter 3 The Colored Bodies of Cell Nuclei: Chromosomes and Heredity 15
Chapter 4 Boveri and the Somatic Mutation Theory of Cancer 23
Chapter 5 Cytogenetics from 1914 to 1960: Slow Progress Followed by Serendipitous Methodological Breakthroughs Leading to Important Discoveries 29
Chapter 6 The First Cancer-Specific Chromosome Aberrations: Ph1 and Others 41
Part II Present 57
Chapter 7 The Banding Revolution: Cancer Cytogenetics in the 1970s 59
Chapter 8 Chasing Correlations: Chromosomes and Oncogenes in Leukemias and Lymphomas 75
Chapter 9 Solid Tumor Cytogenetics 87
Chapter 10 Gains, Losses, and Rearrangements of Genomic Material: Pathogenetic Considerations 105
Chapter 11 Morphology Meets Chemistry: Integration of Molecular Genetics into the Cytogenetic Search for Cancer-Specific Chromosome Aberrations 117
Chapter 12 Unraveling the Clonal Evolution of Neoplastic Cell Populations 125
Chapter 13 Clinical Usefulness 137
Part III Future 149
Chapter 14 Toward a Pathogenetic Classification of Cancer 151
Chapter 15 Where There is Structure, There is Function 161
Chapter 16 Which Resolution Level is Optimally Suited to
Answer Which Questions? Seeing Never Goes Out of Fashion . . . 169
Chapter 17 Are New Technical Breakthroughs on the Horizon? 179
Afterthoughts 189
Index 195
Part I Past 1
Chapter 1 Understanding Disease: Ancient Theories 3
Chapter 2 The Advent of Cellular Pathology 7
Chapter 3 The Colored Bodies of Cell Nuclei: Chromosomes and Heredity 15
Chapter 4 Boveri and the Somatic Mutation Theory of Cancer 23
Chapter 5 Cytogenetics from 1914 to 1960: Slow Progress Followed by Serendipitous Methodological Breakthroughs Leading to Important Discoveries 29
Chapter 6 The First Cancer-Specific Chromosome Aberrations: Ph1 and Others 41
Part II Present 57
Chapter 7 The Banding Revolution: Cancer Cytogenetics in the 1970s 59
Chapter 8 Chasing Correlations: Chromosomes and Oncogenes in Leukemias and Lymphomas 75
Chapter 9 Solid Tumor Cytogenetics 87
Chapter 10 Gains, Losses, and Rearrangements of Genomic Material: Pathogenetic Considerations 105
Chapter 11 Morphology Meets Chemistry: Integration of Molecular Genetics into the Cytogenetic Search for Cancer-Specific Chromosome Aberrations 117
Chapter 12 Unraveling the Clonal Evolution of Neoplastic Cell Populations 125
Chapter 13 Clinical Usefulness 137
Part III Future 149
Chapter 14 Toward a Pathogenetic Classification of Cancer 151
Chapter 15 Where There is Structure, There is Function 161
Chapter 16 Which Resolution Level is Optimally Suited to
Answer Which Questions? Seeing Never Goes Out of Fashion . . . 169
Chapter 17 Are New Technical Breakthroughs on the Horizon? 179
Afterthoughts 189
Index 195
Este título pertence ao(s) assunto(s) indicados(s). Para ver outros títulos clique no assunto desejado.
